Harald Gröger Selected Research

Nitriles

1/2022	Crystal structural analysis of aldoxime dehydratase from Bacillus sp. OxB-1: Importance of surface residues in optimization for crystallization.
1/2022	Process Development of the Copper(II)-Catalyzed Dehydration of a Chiral Aldoxime and Rational Selection of the Co-Substrate.
3/2021	Synthetic Processes toward Nitriles without the Use of Cyanide: A Biocatalytic Concept Based on Dehydration of Aldoximes in Water.
1/2021	Rationalizing the Unprecedented Stereochemistry of an Enzymatic Nitrile Synthesis through a Combined Computational and Experimental Approach.
1/2018	Biocatalytic Synthesis of Nitriles through Dehydration of Aldoximes: The Substrate Scope of Aldoxime Dehydratases.
1/2017	Cyanide-Free and Broadly Applicable Enantioselective Synthetic Platform for Chiral Nitriles through a Biocatalytic Approach.

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Harald Gröger Research Topics

Disease

9	Dehydration (Water Stress) 01/2022 - 01/2017
1	Multiple Sclerosis 01/2019
1	Neoplasms (Cancer) 11/2018

Drug/Important Bio-Agent (IBA)

6	NitrilesIBA 01/2022 - 01/2017
6	OximesIBA 01/2022 - 01/2017
4	aldoxime dehydrataseIBA 01/2022 - 01/2019
4	acetaldehyde oxime (acetaldoxime)IBA 01/2022 - 01/2018
3	EnzymesIBA 01/2022 - 01/2019
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2019
2	AldehydesIBA 01/2022 - 01/2019
2	Cyanides (Isocyanides)IBA 03/2021 - 01/2017
2	Hydro-Lyases (Dehydratases)IBA 11/2018 - 01/2018
1	MetalsIBA 01/2022
1	prolinalIBA 01/2022
1	saxagliptin FDA Link 01/2022
1	VildagliptinIBA 01/2022
1	CopperIBA 01/2022
1	Heme (Haem)IBA 01/2022
1	cupric acetate (copper(II) acetate)IBA 01/2022
1	EmulsionsIBA 01/2021
1	Hydroxylamine (Hydroxylamine Hydrochloride)IBA 01/2019
1	ozanimodIBA 01/2019
1	2-(2'-pyridyldithio)benzyldiazoacetateIBA 11/2018